In Dragon Quest VIII: Sora to Umi to Daichi to Norowareshi Himegimi you can play as a young guardsman who must fight against a curse that he is mysteriously immune to. Characters in the game are designed by the creator of the Dragonball characters and are cel-shaded to provide an "anime" feel. The game is set in a large 3D world ravaged by the effects of the curse.
NOTE: To play this game you will require a Japanese PlayStation 2 and some knowledge of Japanese. This game is also playable on a computer using the PCXS2 emulator.